Camptothecin

Published date: Oct 17, 2018   Tags: 7689-03-4 Camptothecin Camptotheca acuminata

Camptothecin is an alkaloid derived from the Chinese tree Camptotheca acuminata Decne. Camptotheca acuminata extract and its derivatives are unique in their ability to inhibit DNA Topoisomerase I, by stabilizing a covalent reaction intermediate termed the cleavable complex which ultimately causes tumor cell death.